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의료진 소개

김예신 의사

김예신 교수

신경과(뇌신경센터), 뇌신경센터 관심의료진 등록

전문 진료 분야

퇴행성뇌질환(치매), 기억력 및 인지기능장애, 언어장애, 행동장애, 치매예방

진료 일정

학력사항

  • 성균관대학교 의학박사
  • 강원대학교 의학석사
  • 강원대학교 의과대학 졸업

교육 및 연구경력

  • 2026-현재  | 이대서울병원 신경과 임상부교수
  • 2024-2026  | 강원대학교병원 신경과 조교수
  • 2021-2024  | 강원대학교병원 신경과 기금조교수
  • 2018-2021  | 강원대학교병원 신경과 임상조교수
  • 2016-2018  | 삼성서울병원 신경과 전임의 (행동신경학·치매)
  • 2012-2016  | 강원대학교병원 신경과 전공의 수료

수상경력

  • 2025 | 대한인지중재치료학회 우수포스터발표상 (교신저자)
  • 2024 | 대한치매학회 연구지원상
  • 2019 | 대한치매학회 연구지원상
  • 2017 | 대한치매학회 우수포스터발표상

기타 학술 관련 경력

  • 2026-현재  | 대한치매학회 연수위원
  • 2025-현재  | 대한신경과학회 편집위원 (Journal of Clinical Neurology)
  • 2025-현재  | 대한치매학회 간행위원 (Dementia and Neurocognitive Disorders)
  • 2024-2026  | 대한치매학회 국제협력위원
  • 2022-현재  | 대한치매학회 정도관리위원
  • 2024-2025  | 대한신경과학회 수련위원
  • 2013-현재  | 대한치매학회 정회원
  • 2012-현재  | 대한신경과학회 정회원

논문

  •  Plasma Phosphorylated Tau 217 Cutoffs for Amyloid Pathology and Kidney Function, Body Mass Index, and Anemia..  JAMA Neurol. 2026-03. 
  •  Efficacy and Safety of Mobile App–Based Metamemory Cognitive Training for Mild Cognitive Impairment: Multicenter Randomized Clinical Trial.  JMIR mHealth and uHealth. 2026-01. 
  •  Longitudinal association of chronic periodontitis with all-cause dementia, Alzheimer disease, vascular dementia, and mild cognitive impairment: a distributed network analysis..  GeroScience. 2026-03. 
  •  A safer and easier method to open the orbital septum: septal ballooning..  Ophthalmic Plastic & Reconstructive Surgery. 2026-02. 
  •  Reconstructing Neurology Residency Training Program for Essential Medical Discipline: Strategic Directions and Future Challenges..  Journal of the Korean Neurological Association. 2025-12. 
  •  Temporal dynamics and biological variability of Alzheimer biomarkers.  JAMA Neurology. 2025-04. 
  •  Physical activity, Alzheimer plasma biomarkers, and cognition.  JAMA Network Open. 2025-03. 
  •  Differential roles of Alzheimer's disease plasma biomarkers in stepwise biomarker-guided diagnostics.  Alzheimer's & Dementia. 2025-02. 
  •  Gintonin Binds to Reduced LPA4 Receptor Subtype in Human Cortical Neurons in Alzheimer's Disease Brains.  Biomolecules. 2025-02. 
  •  Clinical Practice Guidelines for Dementia: Recommendations for the Pharmacological Treatment of Behavioral and Psychological Symptoms.  Dement Neurocogn Disord. 2025-01. 
  •  Clinical Practice Guidelines for Dementia: Recommendations for Cholinesterase Inhibitors and Memantine [제1저자].  Dement Neurocogn Disord. 2025-01. 
  •  Clinical effects of amyloid positivity upon positron emission tomography in an Asian cohort with Alzheimer's disease and other dementias.  Alzheimers Dement.. 2025-01. 
  •  Ethnic differences in the prevalence of amyloid positivity and cognitive trajectories.  Alzheimers Dement.. 2024-11. 
  •  Factors associated with cognitive reserve according to education level [제1저자].  Alzheimers Dement.. 2024-11. 
  •  Development of the Diagnostic Matrix of the Seoul Cognitive Status Test, Compared to Traditional Paper-and-Pencil Neuropsychological Tests.  Dement Neurocogn Disord. 2024-12. 
  •  Korea-Registries to Overcome Dementia and Accelerate Dementia Research (K-ROAD).  Dement Neurocogn Disord. 2024-12. 
  •  Lower-Body Fractures and the Risk of Dementia: A Nationwide Population-Based Study.  J Clin Neurol.. 2024-03. 
  •  Enrichment of infection-associated bacteria in the low biomass brain bacteriota of Alzheimer's disease patients.  PLoS One. 2024-02. 
  •  The Usefulness of 18F-FDG PET to Differentiate Subtypes of Dementia: The Systematic Review and Meta-Analysis.  Dement Neurocogn Disord. 2024-01. 
  •  Influence of Sensory Impairments on Incidence of Dementia in the Korean Population.  Psychiatry Investig. 2023-06. 
  •  Clinical outcomes of increased focal amyloid uptake in individuals with subthreshold global amyloid levels.  Frontiers in Aging Neuroscience. 2023-03. 
  •  Machine learning application for classification of Alzheimer's disease stages using 18F-flortaucipir PET.  BioMedical Engineering OnLine. 2023-04. 
  •  Deep learning application for the classification of Alzheimer's disease using 18F-flortaucipir (AV-1451) tau PET.  Scientific Reports. 2023-05. 
  •  Machine learning-based automatic estimation of cortical atrophy using brain computed tomography images.  Scientific Reports. 2022-09. 
  •  Transferability of Alzheimer Disease Polygenic Risk Score Across Populations and Its Association With Alzheimer Disease-Related Phenotypes.  JAMA Netw Open. 2022-12. 
  •  Predicting progression to dementia with comprehensive visual rating scale and machine learning algorithms.  Frontiers in Neurology. 2022-08. 
  •  Two cases of non-fluent variant primary progressive aphasia with different pathological diagnoses.  Precision and Future Medicine. 2021-05. 
  •  Effect of education on functional network edge efficiency in Alzheimer's disease [제1저자].  Scientific Reports. 2021-01. 
  •  Disease progression modeling of Alzheimer's disease according to education level.  Scientific Reports. 2020-10. 
  •  The Impact of Amyloid-β or Tau on Cognitive Change in the Presence of Severe Cerebrovascular Disease.  J Alzheimers Dis. 2020-10. 
  •  Depressive symptoms are associated with worse cognitive prognosis in patients with newly diagnosed idiopathic Parkinson disease.  Psychogeriatrics. 2020-11. 
  •  Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients.  Alzheimers Dement.. 2020-11. 
  •  Head-to-Head Comparison of 18F-Florbetaben and 18F-Flutemetamol in the Cortical and Striatal Regions.  J Alzheimers Dis. 2020-07. 
  •  Dynamic association between AT(N) profile and cognition mediated by cortical thickness in Alzheimer's continuum.  Neuroimage Clin.. 2020-05. 
  •  Identifying a subtype of Alzheimer's disease characterised by predominant right focal cortical atrophy.  Scientific Reports. 2020-05. 
  •  Clinical significance of focal ß-amyloid deposition measured by 18F-flutemetamol PET.  Alzheimers Res Ther. 2020-01. 
  •  Reduced forced vital capacity is associated with cerebral small vessel disease burden in cognitively normal individuals [제1저자].  Neuroimage Clin.. 2019-11. 
  •  Staging and quantification of florbetaben PET images using machine learning: impact of predicted regional cortical tracer uptake and amyloid stage on clinical outcomes.  Eur J Nucl Med Mol Imaging. 2019-12. 
  •  A new Centiloid method for 18F-florbetaben and 18F-flutemetamol PET without conversion to PiB.  Eur J Nucl Med Mol Imaging. 2019-08. 
  •  Differences in neuroimaging features of early- versus late-onset nonfluent/agrammatic primary progressive aphasia.  Neurobiol Aging. 2019-10. 
  •  Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients.  Eur J Nucl Med Mol Imaging. 2019-08. 
  •  Sex-specific relationship of cardiometabolic syndrome with lower cortical thickness.  Neurology. 2019-09. 
  •  Prediction of fast decline in amyloid positive mild cognitive impairment patients using multimodal biomarkers.  Neuroimage Clin.. 2019-07. 
  •  Association of Nutritional Status with Cognitive Stage in the Elderly Korean Population.  J Clin Neurol.. 2019-07. 
  •  Cortical atrophy pattern-based subtyping predicts prognosis of amnestic MCI: an individual-level analysis.  Neurobiol Aging. 2019-02. 
  •  Clinical Effects of Frontal Behavioral Impairment: Cortical Thickness and Cognitive Decline in Individuals with Subjective Cognitive Decline and Amnestic MCI.  Journal of Alzheimer's Disease. 2019-01. 
  •  Clinical significance of amyloid β positivity in patients with probable cerebral amyloid angiopathy markers.  Eur J Nucl Med Mol Imaging. 2019-06. 
  •  Functional connectivity associated with tau levels in ageing, Alzheimer's, and small vessel disease.  Brain. 2019-04. 
  •  Non-alcoholic fatty liver disease and cerebral small vessel disease in Korean cognitively normal individuals.  Scientific Reports. 2019-02. 
  •  Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease.  Scientific Reports. 2019-02. 
  •  Amyloid involvement in subcortical regions predicts cognitive decline.  Eur J Nucl Med Mol Imaging. 2018-12. 
  •  The Brain Donation Program in South Korea.  Yonsei Medical Journal. 2018-10. 
  •  Social Event Memory Test (SEMT): A Video-based Memory Test for Predicting Amyloid Positivity for Alzheimer's Disease.  Scientific Reports. 2018-07. 
  •  Vascular Effects on Depressive Symptoms in Cognitive Impairment [제1저자].  Journal of Alzheimer's Disease. 2018-09. 
  •  Pathologically Confirmed Cerebral Amyloid Angiopathy with No Radiological Sign in a Patient with Early Onset Alzheimer's Disease [교신저자].  Yonsei Medical Journal. 2018-07. 
  •  Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 PET Imaging.  JAMA Neurology. 2018-08. 
  •  Machine Learning-based Individual Assessment of Cortical Atrophy Pattern in Alzheimer's Disease Spectrum.  Scientific Reports. 2018-03. 
  •  The Impact of APOE ɛ4 in Alzheimer's Disease Differs According to Age.  Journal of Alzheimer's Disease. 2018-01. 
  •  Prognostic value of amyloid PET scan in normal pressure hydrocephalus.  Journal of Neurology. 2018-01. 
  •  A Nomogram for Predicting Amyloid PET Positivity in Amnestic Mild Cognitive Impairment.  Journal of Alzheimer's Disease. 2018-11. 
  •  Trajectories of Physiological Brain Aging and Related Factors in People Aged from 20 to over 80.  Journal of Alzheimer's Disease. 2018-10. 
  •  Diagonal Earlobe Crease is a Visible Sign for Cerebral Small Vessel Disease and Amyloid-β.  Scientific Reports. 2017-10. 
  •  Distinctive Clinical Effects of Haemorrhagic Markers in Cerebral Amyloid Angiopathy.  Scientific Reports. 2017-11. 
  •  Proposal Guidelines for Standardized Operating Procedures of Brain Autopsy: Brain Bank in South Korea.  Yonsei Medical Journal. 2017-09. 
  •  Correlations between Gray Matter and White Matter Degeneration in Pure Alzheimer's Disease, Pure Subcortical Vascular Dementia, and Mixed Dementia.  Scientific Reports. 2017-08. 
  •  Can Continuous Positive Airway Pressure Reduce the Risk of Stroke in Obstructive Sleep Apnea Patients? A Systematic Review and Meta-Analysis [제1저자].  PLoS One. 2016-01.