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Medical Staff Introduction

Byung Seok Moon

Byung Seok Moon Professor

Nuclear Medicine

Specialized Field of Medicine

Radiochemistry, Radiopharmaceuticals

Operating Hours

Paper

  •  Saengmaeksan, a traditional polyherbal formulation containing Panax ginseng, improves energy metabolism during exercise.  PLOS ONE. 2024. 
  •  Efficacy of preoperative lymphoscintigraphy in predicting surgical outcomes of lymphaticovenous anastomosis in lower extremity lymphedema: Clinical correlations in gynecological cancer-related lymphedema.  PLOS ONE. 2024. 
  •  Value of quantitative salivary gland SPECT/CT for the detection of saliva leakage.  Clinical Nuclear Medicine. 2024. 
  •  The Added Value of SPECT/CT Lymphoscintigraphy in the Initial Assessment of Secondary Extremity Lymphedema Patients.  Scientific Reports. 2023. 
  •  A novel chalcone derivative exerts anticancer effect by apoptotic cell death in human pancreatic cancer cell.  Bioorganic & Medicinal Chemistry. 2023. 
  •  In vivo tissue pharmacokinetics of ERBB2-specific binding oligonucleotide based drugs by PET imaging.  Clinical and Translational Science. 2023. 
  •  Salivary gland uptake of 18F-FP-CIT PET as a new biomarker in patients with Parkinson’s disease.  Korean Journal of Radiology. 2023. 
  •  Clinical impact of SPECT/CT in evaluation of abdominothoracic fistula.  Clinical Nuclear Medicine. 2023. 
  •  Potential utility of SPECT/CT for early detection of spontaneous osteonecrosis of the knee.  Clinical Nuclear Medicine. 2022. 
  •  Feasibility of 18F-fluorocholine PET for evaluating skeletal muscle atrophy in a starved rat model.  Diagnostics. 2022. 
  •  Clinical usefulness of 18F-FET PET in a pediatric patient with suspected Demyelinating disease.  Clinical Nuclear Medicine. 2022. 
  •  Effect of taurine and ginseng extracts on energy metabolism during exercise and their anti-fatigue properties in mice.  Nutrition Research and Practice. 2022. 
  •  Potential anticancer effect of aspirin and 2'-hydroxy-2,3,5'-trimethoxychalcone-linked polymeric micelles against cervical cancer through apoptosis.  Oncology Letters. 2022. 
  •  Tissue pharmacokinetics of DHP107, a novel lipid-based oral formulation of paclitaxel, in mice and patients by positron emission tomography.  Clinical and Translational Science. 2021. 
  •  18F-FET PET/CT as a diagnostic tool for brain abscess.  Clinical Nuclear Medicine. 2021. 
  •  A network pharmacology approach to explore the potential role of Panax ginsengon exercise performance.  Physical Activity and Nutrition. 2021. 
  •  Feasibility of TSPO-specific PET radiotracer for evaluating paracetamol-induced liver injury.  Diagnostics. 2021. 
  •  Radioactive iodine treatment for children and young adults with thyroid cancer in South Korea: A population-based study.  Journal of Clinical Endocrinology and Metabolism. 2021. 
  •  Lymphoscintigraphic findings as indicators of lymphaticovenous anastomosis outcome in patients with extremity lymphedema: A retrospective cohort study.  Clinical Nuclear Medicine. 2021. 
  •  TSPO expression modulatory effect of acetylcholinesterase inhibitor in the ischemic stroke rat model.  Cells. 2021. 
  •  The impact of data-driven respiratory gating in clinical F-18 FDG PET/CT: comparison of free breathing and deep-expiration breath-hold CT protocol.  Annals of Nuclear Medicine. 2021. 
  •  Camphene attenuates skeletal muscle atrophy by regulating oxidative stress and lipid metabolism in rats.  Nutrients. 2020. 
  •  Chlorogenic acid in Viscum albumcallus is a potential anticancer agent against C6 glioma cells.  Pharmacognosy Magazine. 2020. 
  •  99mTc-RBC SPECT/CT for duodenal bleeding point detection.  Clinical Nuclear Medicine. 2020. 
  •  The correlation of salivary gland uptake between 18F-FP-CIT PET/CT and salivary scan.  Clinical Nuclear Medicine. 2020. 
  •  Comparative study in different filters for efficient sterile filtration.  Bulletin of the Korean Chemical Society. 2020. 
  •  Suppressing breast cancer by exercise: consideration to animal models and exercise protocols.  Physical Activity and Nutrition. 2020. 
  •  Neuroprotective effects of a novel Fas-associated factor 1 inhibitor in a Parkinson’s disease model: an [18F]FE-PE2I positron emission tomography analysis study.  Frontiers in Pharmacology. 2020. 
  •  Heat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells.  Korean Journal of Physiology and Pharmacology. 2020. 
  •  A simple decontamination procedure for unintended iodide impurity during [11C]methionine production.  Journal of Radioanalytical and Nuclear Chemistry. 2019. 
  •  Combination of in vivo [123I]FP-CIT SPECT and microdialysis reveals an antipsychotic drug haloperidol-induced synaptic dopamine availability in the rat midbrain and striatum.  Experimental Neurobiology. 2019. 
  •  Theranostic convergence bioradiopharmaceutical for immuno-PET based radioimmunotherapy of L1CAM in cholangiocarcinoma model.  Clinical Cancer Research. 2019. 
  •  Compartmental-modeling-based measurement of murine glomerular filtration rate using 18F-fluoridePET/CT.  Scientific Reports. 2019. 
  •  Synthesis and biological evaluation of tricarbonyl technetium labeled 2-(4-chloro)phenyl-imidazo[1,2-a]pyridine analog (99mTc-CB257) as a TSPO-binding ligand.  Journal of radiopharmaceuticals and molecular probes. 2018. 
  •  Preclinical comparison study between [18F]fluoromethyl-PBR28 and its deuterated analog in a rat model of neuroinflammation.  Bioorganic & Medicinal Chemistry Letters. 2018. 
  •  Remarkable solvent effects of structurally diverse alcohols on nucleophilic displacement with halides.  Bulletin of the Korean Chemical Society. 2018. 
  •  Feasibility of myocardial PET imaging using a benzylguanidine analog: meta-(3-[18F]fluoropropyl)benzylguanidine (18F-mFPBG).  Nuclear Medicine and Biology. 2018. 
  •  Assessment of TSPO in a rat experimental autoimmune myocarditis model: A comparison study between [18F]fluoromethyl-PBR28 and [18F]CB251.  International Journal of Molecular Sciences. 2018. 
  •  Fully automated radiosynthesis of [68Ga]edotreotide ([68Ga]DOTA-TOC) and its quality controls.  Journal of radiopharmaceuticals and molecular probes. 2017. 
  •  The position of fluorine in CP-118,954 affects AChE inhibition potency and PET imaging quantification for AChE expression in the rat brain.  European Journal of Pharmaceutical Sciences. 2017. 
  •  A potential PET radiotracer for the 5-HT2c receptor: Synthesis and in vivo evaluation of 4-(3-[18F]fluorophenethoxy)pyrimidine.  ACS Chemical Neuroscience. 2017. 
  •  Consecutive automated production of 11C-labeled radiopharmaceuticals by sharing 11C-methylation reagent from one 11C-synthetic module.  Journal of radiopharmaceuticals and molecular probes. 2016. 
  •  PET measurement of "GABA shift" in the rat brain: A preclinical application of bolus plus constant infusion paradigm of [18F]flumazenil.  Nuclear Medicine and Biology. 2017. 
  •  Synthesis and in vivo evaluation of a kit-type 99mTc-labeled N-(2-aminoethyl)-3-(4-(2-hydroxy-3-(isopropylaminopropoxy)phenyl)propanamide as a selective beta1-adrenoceptor-binding SPECT radiotracer.  Bulletin of the Korean Chemical Society. 2016. 
  •  Synthesis and evaluation of tricarbonyl 99mTc-labeled 2-(4-chloro)phenylimidazo[1,2-a]pyridine analogs as novel SPECT imaging radiotracer for TSPO-rich cancer.  International Journal of Molecular Sciences. 2016. 
  •  Immuno-PET imaging and radioimmunotherapy of 64Cu-/177Lu-labeled anti-EGFR antibody in esophageal squamous cell carcinoma model.  Journal of Nuclear Medicine. 2016. 
  •  Neuropsychological, metabolic, and GABAA receptor studies in subjects with repetitive traumatic brain injury.  Journal of Neurotrauma. 2016. 
  •  A novel PET imaging probe for the detection and monitoring of translocator protein 18 kDa expression in pathological disorders.  Scientific Reports. 2016. 
  •  Suicidal gene therapy with rabbit cytochrome P450 4B1/2-aminoanthracene or 4-ipomeanol system in human colon cancer cell.  Journal of radiopharmaceuticals and molecular probes. 2015. 
  •  PET imaging of dopamine transporters with [18F]FE-PE2I: Effects of anti-Parkinsonian drugs.  Nuclear Medicine and Biology. 2016. 
  •  Improvement, operation and management status of the KOTRON-13 cyclotron.  Journal of radiopharmaceuticals and molecular probes. 2015. 
  •  Development of an additive [11C]CO2 target system in the KOTRON-13 cyclotron and its application for [11C]radiopharmaceutical production.  Nuclear Instruments and Methods in Physics Research Section B. 2015. 
  •  SPECT/CT imaging of high-Risk atherosclerotic plaques using integrin-binding RGD peptide analogs.  Scientific Reports. 2015. 
  •  In vivo tissue pharmacokinetics of carbon-11-labeled clozapine in healthy volunteers: A positron emission tomography study.  CPT: Pharmacometrics & Systems Pharmacology. 2015. 
  •  Routine production of [18F]flumazenil from iodonium tosylate using a sample pretreatment method: a 2.5-year production report.  Molecular Imaging and Biology. 2014. 
  •  Synthesis and in vivo evaluation of 5-methoxy-2-(phenylethynyl)quinoline (MPEQ) and [11C]MPEQ targeting metabotropic glutamate receptor 5 (mGluR5).  Bulletin of the Korean Chemical Society. 2014. 
  •  [18F]Fluoromethyl-PBR28 as a potential radiotracer for TSPO: Preclinical comparison with [11C]PBR28 in a rat model of neuroinflammation.  Bioconjugate Chemistry. 2014. 
  •  Proof of mechanism study of a novel serotonin transporter blocker, DA-8031, using [11C]DASB positron emission tomography and in vivo microdialysis.  Urology. 2014. 
  •  Synthesis and evaluation of fluorine-18 labeled 4-ipomeanol as an imaging agent for CYP4B1 gene prodrug activation therapy.  Cancer Biotherapy and Radiopharmaceuticals . 2013. 
  •  Synthesis and biological evaluation of RGD peptides with the 99mTc/188Re chelated iminodiacetate core: Highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis.  RSC advances. 2013. 
  •  Production of 11C labeled radiopharmaceuticals using [11C]CO2 production in the KOTRON-13.  The Korean Journal of Nuclear Medicine Technology. 2012. 
  •  Facile aromatic radiofluorination of [18F]flumazenil from diaryliodonium salts with evaluation of their stability and selectivity.  Organic & Biomolecular Chemistry. 2011. 
  •  Development and optimization of C-11 gas target system in KOTRON-13 cyclotron.  The Korean Journal of Nuclear Medicine Technology. 2011. 
  •  The use of sodium chlorate/hydrochloric acid mixtures as a novel and selective chlorination agent.  Bulletin of the Korean Chemical Society. 2011. 
  •  Aromatic radiofluorination and biological evaluation of 2-aryl-6-[18F]fluorobenzothiazoles as a potential positron emission tomography imaging probe for beta-amyloid.  Bioorganic & Medicinal Chemistry. 2011. 
  •  Intensification of the KOTRON-13 cyclotron by optimizing the ion source.  Journal of the Korean Physical Society. 2010. 
  •  Highly efficient production of [18F]fallypride using small amounts of base concentration.  Applied Radiation and Isotopes. 2010. 
  •  Comparison of D-[18F]FMAU and L-[18F]FMAU as PET imaging agents for HSV1-TK gene expression.  Bulletin of the Korean Chemical Society. 2010. 
  •  Automated synthesis of [18F]fallypride for routine clinical use.  The Korean Journal of Nuclear Medicine Technology. 2010. 
  •  Combined radionuclide-chemotherapy and in vivo imaging of hepatocellular carcinoma cells after transfection of a triple-gene construct, NIS, HSV1-sr39tk, and EGFP.  Cancer Letters. 2010. 
  •  Comparison of 18F-FDG, 18F-FET and 18F-FLT for differentiation between tumor and inflammation in rats.  Nuclear Medicine and Biology. 2009. 
  •  Synthesis and evaluation of aryl-substituted diarylpropionitriles, selective ligands for estrogen receptor beta, as positron-emission tomographic imaging agents.  Bioorganic & Medicinal Chemistry. 2009. 
  •  A novel aromatic fluorine-18 labeling method using iodonium salts precursor.  Nuclear Medicine and Molecular Imaging. 2009. 
  •  Synthesis and evaluation of estrogen receptor beta-selective ligands: Fluoroalkylated indazole estrogens.  Bulletin of the Korean Chemical Society. 2008. 
  •  Synthesis and evaluation of F-18 labeled 2'-deoxy-2'-fluoro-5-methyl-1-β-L-arabinofuranosyluracil (L-[18F]FMAU).  Bulletin of the Korean Chemical Society. 2007. 
  •  Synthesis of novel phytosphingosine derivatives and their preliminary biological evaluation for enhancing radiation therapy.  Bioorganic & Medicinal Chemistry Letters. 2007. 
  •  Synthesis and biologic evaluation of I-123 labeled porphyrin derivative as a tumor imaging agent.  Cancer Biotherapy and Radiopharmaceuticals . 2007. 
  •  Synthesis and evaluation of cis-1-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-5-[124I]iodouracil: A new potential PET imaging agent for HSV1-tk expression.  Journal of Medicinal Chemistry. 2007. 
  •  Syntheses of F-18 labeled fluoroalkyltyrosine derivatives and their biological evaluation in rat bearing 9L tumor.  Bioorganic & Medicinal Chemistry Letters. 2007. 
  •  A study on preparation of 3'-[18F]fluoro-3'-deoxythymidine and its biodistribution in 9L tumor bearing rats.  Nuclear Medicine and Molecular Imaging. 2006. 
  •  Synthesis and preliminary evaluation of 9-(4-[18F]fluoro-3-hydroxymethylbutyl)guanine ([18F]FHBG) in HSV1-tk gene transduced hepatoma cell.  Nuclear Medicine and Molecular Imaging. 2006. 
  •  Production of [18F]F2 gas for electrophilic substitution reaction.  Nuclear Medicine and Molecular Imaging. 2006. 
  •  Preparation of 3'-deoxy-3'-[18F]fluorothymidine ([18F]FLT) in ionic liquid, [bmim][OTf].  Journal of Labelled Compounds and Radiopharmaceuticals. 2006. 
  •  Synthesis of F-18 labeled capecitabine using [18F]F2 gas as a tumor imaging agent.  Bulletin of the Korean Chemical Society. 2005. 
  •  Efficient methods for the synthesis of 5-(4-[18F]fluorophenyl)-10,15,20-tris(3-methoxyphenyl)porphyrin as a potential imaging agent for tumor.  Journal of Labelled Compounds and Radiopharmaceuticals. 2005. 
  •  Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter: Part 4. 3-Alkyl-4-halo-6-nitro-quipazine.  Bioorganic & Medicinal Chemistry. 2005. 
  •  Synthesis of O-(3-[18F]fluoropropyl)-L-tyrosine (L-[18F]FPT) and its biological evaluation in 9L tumor bearing rat.  Bulletin of the Korean Chemical Society. 2005. 
  •  Synthesis and binding affinities of fluoroalkylated raloxifenes.  Bioorganic & Medicinal Chemistry. 2003. 
  •  Tyrosine derivatives and pharmaceutical compositions containing the same.  10-0706760 (KR).  
  •  Processes for preparing tyrosine derivatives .  10-0706761 (KR).  
  •  Iodouracil derivatives and pharmaceutical compositions containing the same .  10-0740343 (KR).  
  •  Novel phytosphingosine derivatives and their use for enhancing radiation therapy .  10-0823146 (KR).  
  •  Intermediate for the preparation of iodouracil derivatives and process for the preparation thereof.  10-0850636 (KR).  
  •  Porphyrin derivatives, processes for the preparation thereof, and pharmaceutical compositions comprising the same.  10-0962267 (KR).  
  •  Radiotracer introduced [18F]fluoromethyl group targeting neuroinflammationfor PET imaging and synthesis of radiotracer and its biological evaluation method for radiotracer introduced [18F]fluoromethyl group targeting neuroinflammation for PET imaging.  10-1602912 (KR).  
  •  Processes for preparing [18F]flumazenil from diaryliodonium salt precursor.  10-1441406 (KR), 8,895,727 (US), 6035328 (JP), ZL201180072352.2 (CN), 2719387 (EU).  
  •  Method for preparing [18F]fallypride with low base concentration.  10-1051084 (KR), 8,624,039 (US).  
  •  Tricarbonyl Tc or Re labeled cyclic RGD derivatives or pharmaceutically acceptable salts thereof, preparation method thereof, and phrmaceutical composition for the diagnosis or treatment of tumor containing the same as an active ingredient.  10-1383655 (KR), 9,439,986 (US), 5774687 (JP), ZL201180031236.6 (CN), 2583966 (EU).  
  •  mGluR5 radiotracer composition.  10-1579496 (KR).  
  •  Synthesis method of 5-HT2C receptor-specific PET radiotracer.  10-1828868 (KR).